ANALYTE SENSING DEVICE HAVING ONE OR MORE SENSING ELECTRODES

• US 20080249383A1
• Filed: 04/04/2008
• Published: 10/09/2008
• Est. Priority Date: 04/04/2007
• Status: Abandoned Application

• Current Assignee: Konamite Limited
• Original Assignee: Isense Corporation
• Inventors: Sass, Richard G., Ward, W. Kenneth, Bruce, Robert, Kaplan, Daniel M.
• Application Number:
  US12/062,969
• Publication Number:
  US 20080249383A1
• Time in Patent Office: Days
• US Class Current: 600/345
• CPC Class Codes: A61B 17/3468 for implanting or removing devices, e.g. prostheses, implants, seeds, wires devices for implanting seeds A61M37/0069
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/6848 Needles
• CPC Class Codes: A61B 5/6849 in combination with a needle set

Abstract

Embodiments of the present invention provide an analyte sensing device having one or more sensing electrodes. In embodiments, each sensing electrode may serve as an anode, a cathode, or a combination of an anode and cathode. In embodiments, there may be any suitable number of electrodes. Related analyte sensor insertion aids and methods of using the disclosed embodiments are also provided.

Claims

1. An analyte sensing device, comprising:

a main body configured to reside on skin of an individual when in use, the main body having one or more electrical components; and

an analyte sensing electrode extending substantially perpendicularly from and electrically coupled to the main body, the analyte sensing electrode configured for insertion into the skin of the individual.

2. The analyte sensing device of claim 1, wherein the analyte sensing electrode is an anode.

3. The analyte sensing device of claim 1, wherein a skin-contact surface of the main body is a cathode.

4. The analyte sensing device of claim 3, wherein the skin-contact surface of the main body comprises surface protrusions which comprise the cathode.

5. The analyte sensing device of claim 1, wherein the analyte sensing electrode is a combination anode and cathode.

6. The analyte sensing device of claim 1, wherein the analyte sensing electrode extends from the main body by approximately 4-6 mm.

7. The analyte sensing device of claim 1, wherein the main body is a flexible substrate.

8. The analyte sensing device of claim 1, further comprising patterned adhesive on a skin-contact surface of the main body.

9. The analyte sensing device of claim 1, further comprising adhesive on a skin-contact surface of the main body, wherein the adhesive contains silver/silver chloride.

10. An analyte sensing device, comprising:

a main body configured to reside on skin of an individual when in use, the main body having one or more electrical components; and

a plurality of analyte sensing electrodes extending from and electrically coupled to the main body, the analyte sensing electrodes configured for insertion into the skin of the individual.

11. The analyte sensing device of claim 10, wherein the plurality of analyte sensing electrodes comprise at least one anode separate from at least one cathode.

12. The analyte sensing device of claim 10, wherein the plurality of analyte sensing electrodes comprise a plurality of anodes and a skin-contact surface of the main body is a cathode.

13. The analyte sensing device of claim 10, wherein the plurality of analyte sensing electrodes extend substantially perpendicularly from the main body.

14. The analyte sensing device of claim 10, wherein the plurality of analyte sensing electrodes are configured to detecting multiple analytes.

15. A method for measuring analyte in an individual, comprising:

inserting a portion of an analyte sensing device into skin of an individual, the analyte sensing device comprising

a main body configured to reside on the skin of the individual when in use, the main body having one or more electrical components; and

a plurality of analyte sensing electrodes extending from and electrically coupled to the main body, the analyte sensing electrodes configured for insertion into the skin of the individual; and

measuring an amount of analyte detected directly or indirectly by one or more of the plurality of analyte sensing electrodes.

16. The method of claim 15, wherein measuring an amount of analyte detected directly or indirectly by one or more of the plurality of analyte sensing electrodes comprises calculating an analyte sensing electrode average value for two or more of the plurality of analyte sensing electrodes.

17. The method of claim 16, wherein a particular analyte sensing electrode analyte value outside a predetermined acceptable range of values around the calculated average value of remaining analyte sensing electrodes of the plurality of analyte sensing electrodes is disregarded in determining the analyte sensing electrode average value.

18. An analyte sensing electrode insertion aid, comprising:

a base configured to reside on skin of an individual when in use, the main body having at least one hole passing from an upper portion to a lower portion of the base; and

a hollow trocar extending substantially perpendicularly from and coupled to the base, the trocar providing a hole that couples to the hole of the base such that a passage is provided from the upper portion of the base through the base and through the trocar, the passage configured to directionally guide an analyte sensing electrode into skin of the individual.

19. The analyte sensing electrode insertion aid of claim 18, wherein the base is configured to couple with an analyte sensing device having a main body and an extended analyte sensing electrode.

20. The analyte sensing electrode insertion aid of claim 18, wherein the trocar is constructed of sharpened metal or plastic.

21. The analyte sensing electrode insertion aid of claim 18, wherein the trocar is constructed of a material having a temperature-dependent structural integrity such that the trocar is substantially rigid at room temperature but relatively soft at body temperature.

22. The analyte sensing electrode insertion aid of claim 18, wherein the trocar is approximately 1-5 mm in length.

23. An analyte sensing device, comprising:

a main body having one or more electrical components, the main body having a plurality of analyte sensing electrodes extending therefrom and electrically coupled thereto; and

an outer support sleeve having an interior cavity, wherein the main body is movable within the interior cavity and movable with respect to the outer support sleeve from a position in which the plurality of analyte sensing electrodes are fully retracted into the interior cavity to a position in which the plurality of analyte sensing electrodes are extended from the outer support sleeve.

24. The analyte sensing device of claim 23, wherein the outer sleeve further comprises a barrier that must be pierced by the plurality of sensing electrodes when moved from a fully retracted position to an extended position.