Vascular closure device having sensor

• US 20090177225A1
• Filed: 01/25/2008
• Published: 07/09/2009
• Est. Priority Date: 01/26/2007
• Status: Abandoned Application

• Current Assignee: Endotronix, Inc.
• Original Assignee: Endotronix, Inc.
• Inventors: Nunez, Anthony, Rowland, Harry D.
• Application Number:
  US12/011,502
• Publication Number:
  US 20090177225A1
• Time in Patent Office: Days
• US Class Current: 606/213
• CPC Class Codes: A61B 2017/00606 Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/02152 specially adapted for venous pressure
• CPC Class Codes: A61B 5/6862 Stents
• CPC Class Codes: A61B 5/6876 Blood vessel
• CPC Class Codes: A61B 5/6882 Anchoring means

Abstract

A vascular closure device including a first retainer positioned on an internal surface of a vessel wall defining a passage through a vessel. A second retainer is coupled to the first retainer and positioned on an outer surface of the vessel wall to seal an opening defined through the vessel wall. A sensor is coupled to the first retainer and configured to sense a physical, chemical, and/or physiological parameter within the passage.

Claims

1. A vascular closure device comprising:

a first retainer positioned on an internal surface of a vessel wall defining a passage through a vessel;

a second retainer coupled to said first retainer and positioned on an outer surface of the vessel wall to seal an opening defined through the vessel wall; and

a sensor coupled to said first retainer and configured to sense at least one of a physical, chemical, and physiological parameter within the passage.

2. A vascular closure device in accordance with claim 1 further comprising an anchoring member positioned within the opening and coupling said first retainer to said second retainer.

3. A vascular closure device in accordance with claim 1 wherein said sensor is coupled to a radially inner surface of said first retainer.

6. A vascular closure device in accordance with claim 1 wherein said sensor is integrated with said first retainer.

7. A vascular closure device in accordance with claim 6 wherein, upon dissolution of said first retainer, said sensor is coupled to the internal surface of the vessel wall.

8. A vascular closure device in accordance with claim 1 wherein said sensor comprises a capacitor inductor circuit arranged in a parallel configuration and forming an LC tank circuit, said LC tank circuit having a resonating frequency emitted through the vessel and deciphered through an external device to generate an output representative of a parameter within the passage.

9. A vascular closure device in accordance with claim 8 wherein said sensor is fabricated utilizing a microelectromechanical systems (MEMS) technology.

10. A vascular closure device in accordance with claim 1 wherein said sensor comprises one of a capacitive pressure sensing device, a piezoelectric pressure sensing device and a piezoresistive pressure sensing device.

11. A vascular closure device in accordance with claim 1 wherein with said vascular closure device coupled to the vessel wall at a puncture site, said sensor attaching to the vessel wall.

12. A vascular closure device in accordance with claim 1 wherein at least a portion of said sensor is coated with at least one biocompatible material.

13. A vascular closure device in accordance with claim 12 wherein said at least a portion of said sensor is coated with at least one biocompatible polymer.

14. A vascular closure device in accordance with claim 12 wherein said at least one biocompatible material comprises a slow release polymer impregnated with an anti-metabolite inhibiting in-tissue growth, a drug eluting material that prohibits in-tissue growth on said sensor, and a material promoting in-tissue growth on said sensor to facilitate attaching said sensor to the vessel wall.

15. A vascular closure device in accordance with claim 1 wherein a first portion of said sensor is coated with a material prohibiting in-tissue growth on said sensor and a second portion of said sensor is coated with a material promoting the in-tissue growth on said sensor to facilitate attaching said sensor to the vessel wall.

16. A vascular closure device in accordance with claim 1 further comprising an anchoring device coupling said first retainer to said second retainer, at least one of said first retainer, said second retainer, and said anchoring device comprising a non-degradable biocompatible material.

17. A vascular closure device in accordance with claim 1 further comprising a patch applied to an outer skin surface of the patient, said patch in electrical communication with said sensor.

4. (canceled)

5. (canceled)

18. A vascular closure device comprising:

an inner retainer positioned on an internal surface of a vessel wall defining a passage through a vessel, said inner retainer comprising a wireless sensor configured to sense at least one of a physical, chemical, and physiological parameter within the passage; and

an outer retainer coupled to said inner retainer and positioned on an outer surface of the vessel wall to seal an opening defined through the vessel wall.

19. A vascular closure device in accordance with claim 18 wherein said inner retainer comprises:

an electrically conducting surface patterned in a void formed in a radially inner surface of said inner retainer; and

a plate coupled to said radially inner surface to enclose said void and form a hermetically sealed cavity, an inductor component and a capacitor plate patterned on said plate, said electrically conducting surface, said inductor, and said capacitor plate operatively coupled to form an LC tank circuit.

20. A vascular closure device in accordance with claim 19 wherein said inductor and said capacitor plate are electrically coupled in a parallel circuit.

21. A vascular closure device in accordance with claim 19 wherein said plate is configured to deform when a pressure is applied to said plate, the deformation producing a change in capacitance that causes a change in a resonant frequency of the LC tank circuit.

22. A vascular closure device in accordance with claim 19 wherein a resonant frequency of the LC tank circuit is monitored remotely with an external device.

23. A method for treating cardiovascular disease, said method comprising:

positioning a sensor within a passage defined by a vessel wall, the sensor configured to generate a signal representative of at least one of a physical, chemical, and physiological parameter within a vascular system of a patient;

communicating the signal to a patient signaling device located at least partially externally to the patient; and

processing the signal within the patient signaling device to generate at least one instructive treatment signal to facilitate determining a pharmaceutical therapy.

24. A method in accordance with claim 23 further comprising controlling delivery of the pharmaceutical therapy based at least partially on the processed signal.

25. A vascular closure device comprising at least one sensor configured for measuring at least one of a physical, chemical, and physiological parameter of a patient.

26. A vascular closure device in accordance with claim 25 wherein said at least one of a physical, chemical, and physiological parameter includes at least one of a pressure, a temperature, and a cardiac output.

27. A method for measuring at least one of a physical, chemical, and physiological parameter of a patient comprising placing a permanent implant with respect to a vessel wall.

28. A device for measuring at least one of a physical, chemical, and physiological parameter of a patient comprising a sensor permanently implanted in proximity to a vessel wall.

29. A device in accordance with claim 28 wherein said sensor is coupled to one of an outer surface of said vessel wall and an inner surface of said vessel wall.

30. A single-piece flexible vascular closure device comprising:

a first portion positioned within a vessel at an interface of said vascular closure device and a flow of blood through the vessel;

a second portion transitioning into said first portion, at a transition area, at least one of said first portion and said second portion forming a groove configured to receive a portion of a vessel wall defining an opening through the vessel wall, said second portion positioned on an outer surface of the vessel wall to seal the opening; and

a sensor operatively coupled to one of said inner portion and said outer portion, said sensor configured to sense at least one of a physical, chemical, and physiological parameter within the vessel,

31. A single-piece flexible vascular closure device in accordance with claim 30 wherein said sensor is one of directly coupled to said first portion and integrated with said first portion.

32. An implantable monitoring device positionable externally about a vessel, said implantable monitoring device comprising at least one of a load cell and a sensor configured to sense at least one of a physical, chemical, and physiological parameter within the vessel.

33. An implantable monitoring device in accordance with claim 32 further comprising a hinge portion to facilitate fitting said implantable monitoring device about a vessel wall.

34. An implantable monitoring device in accordance with claim 32 wherein at least a portion of said implantable monitoring device is fabricated from at least one of a material having shape memory properties and a polymeric material.

35. An implantable monitoring device in accordance with claim 32 wherein said sensor is configured to sense at least one of a physical, chemical, and/or physiological parameter within the vessel.

36. An implantable monitoring device in accordance with claim 35 wherein said sensor comprises one a pressure sensor, an optical sensor, a biochemical sensor, a protein sensor, a motion sensor, an accelerometer, a gyroscope, a temperature sensor, a chemical sensor, a pH sensor, and a genetic sensor.

37. An implantable monitoring device in accordance with claim 32 wherein said at least one of a load cell and a sensor is fabricated using a microelectromechanical systems (MEMS) technology.

38. An implantable monitoring device in accordance with claim 32 further comprising a RFID/magnetic/antenna component operatively coupled with said at least one of a load cell and a sensor, said RFID/magnetic/antenna component operatively coupled to an external receiver.

39. An implantable device comprising:

a first material defining a void on a first surface, and an electrically conducting surface patterned in said first surface within said void; and

a plate coupled to said first surface to enclose said void, forming a hermetically sealed cavity, said plate patterned with electrically functional components, said implantable device having pressure sensing capabilities.