Interferometric Measuring Instrument for Taking Optical Measurements on Skin Structures

• US 20090247842A1
• Filed: 03/20/2007
• Published: 10/01/2009
• Est. Priority Date: 05/04/2006
• Status: Abandoned Application

• Current Assignee: Robert Bosch GmbH
• Original Assignee: Robert Bosch GmbH
• Inventors: Kallmann, Ulrich
• Application Number:
  US12/227,052
• Publication Number:
  US 20090247842A1
• Time in Patent Office: Days
• US Class Current: 600/316
• CPC Class Codes: A61B 5/0064 Body surface scanning
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/441 Skin evaluation, e.g. for skin disorder diagnosis

Abstract

An interferometric measuring instrument for taking optical measurements on skin structures, having a beam splitter for splitting an input beam, emitted by a light source, into an object beam and a reference beam; having an object branch via which the object beam is directed to the skin, and the object beam, scattered back from the skin structures, is returned; having a reference branch via which the reference beam is directed to a reference and returned from it; and having a detector device for picking up the recombined and interfering radiation of the back-scatted object beam and of the returned reference beam and for evaluating the intensity modulation obtained due to the interference. The following measures contribute significantly to a reliable and rapid optical measurement, e.g., of the blood-sugar concentration: In order to scatter back a portion of the object beam directed into the skin, an implant having a front side facing the incident object beam and a back side facing away from it is introduced into the skin, the implant having a refractive index different from the surrounding skin substance.

Claims

1-8. -8. (canceled)

9. An interferometric measuring instrument for taking optical measurements on skin structures of skin, comprising:

a beam splitter for splitting an input beam, emitted by a light source, into an object beam and a reference beam;

an object branch via which the object beam is directed to the skin, and the object beam, scattered back from the skin structures, is returned;

a reference branch via which the reference beam is directed to a reference and returned from the reference; and

a detector device for picking up recombined and interfering radiation of the back-scattered object beam and of the returned reference beam and for evaluating an intensity modulation obtained due to the interference; and

an implant introduced into the skin for scattering back a portion of the object beam directed into the skin, the implant having a front side facing the incident object beam and a back side facing away from the incident object beam, the implant having a refractive index different from a surrounding skin substance.

10. The measuring instrument according to claim 9, further comprising a scanning device for effectuating a depth scan in the skin and thereby for producing the intensity modulation, the scanning device being set up in such a way that an optical path length of the reference beam in the reference branch or a wavelength of the light source is altered in a predefined manner, or that a spectral resolution and evaluation are carried out in the detector device, in the course of which, a conversion into a local space is performed.

11. The measuring instrument according to claim 9, wherein the implant has a multitude of boundary surfaces relative to a tissue fluid between its front side and its back side, and the evaluation is planned in such a way that, with respect to the passage of the object beam through the implant, at least one of (a) a depth-dependent decrease of the scattered light and (b) an average optical path length is ascertained on the basis of an intensity modulation in an interference signal, accompanied by evaluation of an average refractive index for determining a property of the skin structure.

12. The measuring instrument according to claim 9, wherein the implant is formed, structured or coated in such a way that a front-side signal coming from its front side and a back-side signal coming from its back side are prominent.

13. The measuring instrument according to claim 9, further comprising a dispersion-compensating medium matched to a passage section of the skin and introduced into the reference branch.

14. The measuring instrument according to claim 9, wherein the optical measurements are for determining a blood-sugar concentration.

16. The method according to claim 14, further comprising, to determine the property of the skin structures on the basis of the intensity modulation, ascertaining at least one of (a) a depth-dependent decrease of the scattered light and (b) an average optical path length within the implant, from an evaluation of an average refractive index, in doing so, a geometric wavelength being known.

15. An interferometric method for taking optical measurements on skin structures of skin, comprising:

splitting an input beam coming from a light source into a reference beam guided to a reference and an object beam guided to the skin;

bringing to interference the reference beam and the object beam scattered back from the reference and from the skin;

detecting and evaluating an intensity modulation obtained due to the interference for determining a property of the skin structures;

introducing an implant that has a refractive index different from a surrounding skin substance into the skin; and

evaluating the intensity modulation brought about by light scattered back at at least one boundary surface of the implant relative to tissue fluid for determining the property of the skin structures.

17. The method according to claim 15, wherein the optical measurements are for determining a blood-sugar concentration.