Non-invasive Cardiac Characteristic Determination System

• US 20100185084A1
• Filed: 01/19/2010
• Published: 07/22/2010
• Est. Priority Date: 01/22/2009
• Status: Abandoned Application

• Current Assignee: Siemens Medical Solutions USA Incorporated (Siemens AG)
• Original Assignee: Siemens Medical Solutions USA Incorporated (Siemens AG)
• Inventors: Zhang, Hongxuan
• Application Number:
  US12/689,331
• Publication Number:
  US 20100185084A1
• Time in Patent Office: Days
• US Class Current: 600/425
• CPC Class Codes: A61B 5/029 Measuring or recording blood output from the heart, e.g. minute volume A61B8/065 takes precedence
• CPC Class Codes: A61B 5/7285 for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal A61B6/5205, A61B6/541, A61B8/5207, A61B8/543 take precedence
• CPC Class Codes: A61B 8/065 to determine blood output from the heart in general A61B5/029

Abstract

A system uses non-invasive laser, ultrasound or electro-magnetic monitoring, to derive CO/SV, CO/SV deviation, and related cardiac function parameters. The non-invasive system determines cardiac stroke volume and includes an input processor for receiving determined values provided using a measurement processor. The determined values comprise, a blood vessel internal diameter and rate of flow of blood through the blood vessel in a heart cycle. A computation processor calculates a vessel stroke volume comprising volume of blood transferred through the blood vessel in a heart cycle using the measured blood vessel internal diameter and the rate of flow of blood. The computation processor determines cardiac stroke volume by determining a factor for use in adjusting the vessel stroke volume to provide a cardiac stroke volume and adjusting the vessel stroke volume using the determined factor to provide the cardiac stroke volume. An output processor provides data representing the determined cardiac stroke volume to a destination.

Claims

1. A non-invasive system for determining cardiac stroke volume, comprising:

an input processor for receiving vital sign signals and hemodynamic signals of a patient,

a computation processor for calculating a heart stroke volume of said patient by applying a factor to a determined vessel stroke volume, said vessel stroke volume being determined as volume of blood transferred through the blood vessel in a heart cycle using the measured blood vessel internal diameter and the rate of flow of blood;

a mapping processor for using predetermined mapping information associating ranges of patient signal values and stroke volume with medical conditions for mapping the received patient vital sign signals and hemodynamic signals and calculated stroke volume to data indicating a medical condition of said patient; and

an output processor for providing data representing the indicated medical condition to a destination device.

2. A system according to claim 1, wherein

said computation processor non-invasively determines said vessel stroke volume by measuring said blood vessel internal diameter and rate of flow of blood through said blood vessel in a heart cycle using an ultrasound imaging system.

3. A non-invasive system for determining cardiac stroke volume, comprising:

an input processor for receiving determined values provided using a measurement processor, said determined values comprising,

a blood vessel internal diameter and

rate of flow of blood through said blood vessel in a heart cycle;

a computation processor for,

calculating a vessel stroke volume comprising volume of blood transferred through the blood vessel in a heart cycle using the measured blood vessel internal diameter and the rate of flow of blood,

calculating cardiac stroke volume by determining a factor for use in adjusting said vessel stroke volume to provide a cardiac stroke volume and

adjusting said vessel stroke volume using the determined factor to provide said cardiac stroke volume; and

an output processor for providing data representing the determined cardiac stroke volume to a destination.

4. A system according to claim 3, wherein

said measurement processor non-invasively measures said blood vessel internal diameter and rate of flow of blood through said blood vessel in a heart cycle using an ultrasound imaging system.

5. A system according to claim 3, wherein

said measurement processor non-invasively measures said blood vessel internal diameter and rate of flow of blood through said blood vessel in a heart cycle using at least one of, (a) a laser based measurement system and (b) a microwave based measurement system.

6. A system according to claim 3, wherein

said computation processor determines said factor from a patient specific look-up table including factor representative data associated with one or more particular patient blood vessels derived for the patient concerned from stroke volume measurements performed on prior occasions.

7. A system according to claim 3, wherein

said factor representative data is derived for the patient concerned using prior invasive stroke volume measurements performed on prior occasions.

8. A system according to claim 3, wherein

said computation processor determines said factor using an artificial neural network.

9. A system according to claim 8, wherein

said artificial neural network is configured using a training data set comprising data for the patient concerned.

10. A system according to claim 8, wherein

said artificial neural network is configured using a training data set selected from a plurality of training data sets using demographic data of the patient concerned.

11. A system according to claim 8, wherein

said demographic data comprises at least two of, age, height, weight, gender and pregnancy status.

12. A system according to claim 3, wherein

said computation processor calculates a cardiac output (CO) value using the determined cardiac stroke volume.

13. A system according to claim 3, wherein

said computation processor determines said factor from a look-up table including factor representative data associated with at least two of, blood vessel diameter, rate of flow of blood through a blood vessel, patient height, patient weight, patient gender, patient race, patient age and patient pregnancy status, location of a vessel in a body.

14. A system according to claim 3, wherein

said measurement processor provides said determined values in response to selection of the vessel in a location including at least one of, (a) a limb, (b) a wrist, (c) a finger and (d) a heart.

15. A non-invasive method for determining cardiac stroke volume, comprising the activities of:

receiving data indicating,

a blood vessel internal diameter and

rate of flow of blood through said blood vessel in a heart cycle;

calculating a vessel stroke volume comprising volume of blood transferred through the blood vessel in a heart cycle using the measured blood vessel internal diameter and the rate of flow of blood,

determining cardiac stroke volume by determining a factor for use in adjusting said vessel stroke volume to provide a cardiac stroke volume and

adjusting said vessel stroke volume using the determined factor to provide said cardiac stroke volume; and

providing data representing the determined cardiac stroke volume to a destination.