Optical Apparatus for Measuring a Physiological Property of a Body Part and Method Therefore

• US 20100210925A1
• Filed: 07/29/2008
• Published: 08/19/2010
• Est. Priority Date: 07/30/2007
• Status: Abandoned Application

• Current Assignee: Lein Applied Diagnostics Limited
• Original Assignee: Lein Applied Diagnostics Limited
• Inventors: Hearn, Austen, Holley, Richard
• Application Number:
  US12/671,229
• Publication Number:
  US 20100210925A1
• Time in Patent Office: Days
• US Class Current: 600/310
• CPC Class Codes: A61B 3/152 for aligning
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters

Abstract

An optical measurement apparatus comprises an optical system (100). The optical system (100) includes a source (102) and a detector (112). The source, when in use, emits a probe beam (116) and the optical system is arranged to direct the probe beam (116) to a location to be measured (114). The detector (112) is arranged to receive a reflected beam (120) from the location to be measured (114).The optical system (100) has a receiving numerical aperture associated therewith and is also arranged so that the probe beam (116) has a probe cone angle corresponding to a probe numerical aperture. The receiving numerical aperture is greater than the probe numerical aperture. Alternatively or additionally, the optical system (100) is arranged to apply a magnification ratio between the detector (112) and the location to be measured (114) so as to minimise deviation of the reflected beam from a receiving axis (119) of the optical system (100).

Claims

1. An optical measurement apparatus comprising:

an optical system comprising;

a source arranged to emit, when in use, a probe beam, the optical system being arranged to direct, when in use, the probe beam to a location to be measured; and

a detector arranged to receive, when in use, a reflected beam from the location to be measured;

wherein

the optical system has a receiving numerical aperture associated therewith, the optical system being further arranged so that, when in use, the reflected beam has a cone angle corresponding to a reflected beam numerical aperture; and

the receiving numerical aperture is greater than the reflected beam numerical aperture.

2. An apparatus as claimed in claim 1, wherein the receiving numerical aperture is provided so as to prevent, when in use, vignetting of the reflected beam, the reflected beam numerical aperture being substantially the same as a probe numerical aperture corresponding to a probe cone angle of the probe beam.

3. An apparatus as claimed in claim 1, wherein a probe numerical aperture corresponding to a probe cone angle of the probe beam is set so as to prevent, when in use, vignetting of the reflected beam as a result of the receiving numerical aperture.

4. An apparatus as claimed in claim 1 or claim 2 or claim 3, wherein:

the optical system has a receiving axis associated with the receiving numerical aperture; and

the receiving numerical aperture is arranged to permit acceptance of the reflected beam when deviated from the receiving axis by up to a predetermined maximum off-axis reflection angle with respect to the receiving axis.

5. An apparatus as claimed in claim 1, wherein the optical system is arranged to constrain a probe numerical aperture corresponding to a probe cone angle of the probe beam so that, when in use, the reflected beam is incident within an acceptance angle of the optical system corresponding to the receiving numerical aperture.

6. An apparatus as claimed in any one of the preceding claims, wherein the optical system comprises an optical path from the source to the detector via the location to be measured.

7. An apparatus as claimed in claim 6, wherein the optical system further comprises an optical element disposed in the optical path.

8. An apparatus as claimed in claim 7, wherein the optical element is a refractive optical element.

9. An apparatus as claimed in claim 7, wherein the optical element is an aperture.

10. An apparatus as claimed in claim 7 or claim 8 or claim 9, wherein the optical element provides the receiving numerical aperture.

11. An apparatus as claimed in any one of claims 1 to 10, wherein the probe numerical aperture is dynamically adaptable.

12. An optical measurement apparatus as claimed in claim 1, further comprising a receiving axis, and wherein the optical system is arranged to apply, when in use, a magnification ratio between the detector and the location to be measured so as to minimise deviation of the reflected beam from the receiving axis.

13. An apparatus as claimed in any one of the preceding claims, wherein a waveguide arrangement comprises at least part of the optical system.

14. A confocal measurement apparatus comprising the optical measurement apparatus as claimed in any one of the preceding claims.

22. An apparatus as claimed in any one of claims 1 to 14 or claims 16 to 21, wherein a physiological body-part comprises the location to be measured.

23. An apparatus as claimed in claim 22, wherein the physiological body-part is an eye.

15. A method of optically measuring a location to be measured, the method comprising:

emitting a probe beam;

directing the probe beam to the location to be measured;

providing an optical system capable of receiving a reflected beam from the location to be measured, the optical system having a receiving numerical aperture associated therewith;

wherein

the reflected beam has a cone angle corresponding to a reflected beam numerical aperture; and

the receiving numerical aperture is greater than the reflected beam numerical aperture.

16. An optical measurement apparatus comprising:

an optical system comprising;

a source arranged to emit, when in use, a probe beam, the optical system being arranged to direct, when in use, the probe beam to a location to be measured;

a detector arranged to receive, when in use, a reflected beam from the location to be measured; and

a receiving axis;

wherein

the optical system is arranged to apply, when in use, a magnification ratio between the detector and the location to be measured so as to minimise, when in use, deviation of the reflected beam from the receiving axis.

17. An optical measurement apparatus as claimed in claim 16, wherein the deviation of the reflected beam is due to misalignment of location to be measured with the receiving axis.

18. An apparatus as claimed in claim 16 or claim 17, wherein the optical system has an object plane and an image plane, the magnification ratio being provided between the object and image planes.

19. An apparatus as claimed in any one of claims 16 to 18, wherein the optical system comprises, when in use, an optical element between the detector and the surface to be measured.

20. An apparatus as claimed in claim 19, wherein the optical element is a refractive optical element.

21. A confocal measurement apparatus comprising the optical measurement apparatus as claimed in any one of claims 16 to 20.

24. An apparatus as claimed in any one of claims 16 to 23, wherein a waveguide arrangement comprises at least part of the optical system.

25. A method of optically measuring a location to be measured, the method comprising:

emitting a probe beam;

directing the probe beam to the location to be measured;

using an optical system having a detector to receive a reflected beam from the location to be measured, the optical system having a receiving axis; and

applying a magnification ratio between the detector and the location to be measured so as to minimise deviation of the reflected beam from the receiving axis.