INHIBITING GSNOR

• US 20100286174A1
• Filed: 05/18/2010
• Published: 11/11/2010
• Est. Priority Date: 03/19/2009
• Status: Abandoned Application

• Current Assignee: Duke University
• Original Assignee: Duke University
• Inventors: Rockman, Howard A., Stamler, Jonathan S.
• Application Number:
  US12/782,059
• Publication Number:
  US 20100286174A1
• Time in Patent Office: Days
• US Class Current: 514/260.1
• CPC Class Codes: A61K 31/40 having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
• CPC Class Codes: A61P 11/00 Drugs for disorders of the respiratory system
• CPC Class Codes: A61P 13/12 of the kidneys
• CPC Class Codes: A61P 9/00 Drugs for disorders of the cardiovascular system
• CPC Class Codes: A61P 9/10 for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Treatment of myocardial infarction to reduce infarct size and organogenesis is provided by administration of agents selected from the group consisting of

Claims

1. A method of treating a patient with myocardial infarction comprising administering, to said patient agent selected from the group consisting of

2. A method of treating a patient with organ failure comprising administering to said patient agent selected from the group consisting of

3. The method of claim 2 where the patient is afflicted with heart failure.

4. The method of claim 2 where the patient is afflicted with lung failure.

5. The method of claim 2 where the patient is afflicted with kidney failure.