Quercetin-Containing Compositions

• US 20100331337A1
• Filed: 06/23/2010
• Published: 12/30/2010
• Est. Priority Date: 07/17/2006
• Status: Active Grant

• Current Assignee: Quercis Pharma AG
• Original Assignee: Quercegen Pharmaceuticals LLC
• Inventors: Lines, Thomas Christian
• Granted Patent: US 8,901,109 B2
• Time in Patent Office: Days
• US Class Current: 514/249
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/352 condensed with carbocyclic rings, e.g. methantheline cannabinoids A61K31/658
• CPC Class Codes: A61K 31/375 Ascorbic acid, i.e. vitamin C; Salts thereof
• CPC Class Codes: A61K 31/445 Non condensed piperidines, e.g. piperocaine
• CPC Class Codes: A61K 45/06 Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• CPC Class Codes: A61P 1/00 Drugs for disorders of the alimentary tract or the digestive system
• CPC Class Codes: A61P 11/00 Drugs for disorders of the respiratory system
• CPC Class Codes: A61P 15/00 Drugs for genital or sexual disorders for disorders of sex hormones A61P5/24; Contraceptives
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 19/02 for joint disorders, e.g. arthritis, arthrosis
• CPC Class Codes: A61P 25/28 for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• CPC Class Codes: A61P 29/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
• CPC Class Codes: A61P 3/00 Drugs for disorders of the metabolism of the blood or the extracellular fluid A61P7/00
• CPC Class Codes: A61P 3/10 for hyperglycaemia, e.g. antidiabetics
• CPC Class Codes: A61P 31/00 Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
• CPC Class Codes: A61P 31/04 Antibacterial agents
• CPC Class Codes: A61P 31/12 Antivirals
• CPC Class Codes: A61P 35/00 Antineoplastic agents
• CPC Class Codes: A61P 37/00 Drugs for immunological or allergic disorders
• CPC Class Codes: A61P 37/06 Immunosuppressants, e.g. drugs for graft rejection
• CPC Class Codes: A61P 9/00 : Drugs for disorders of the cardiovascular system
• CPC Class Codes: C07D 213/80 : in position 3

Abstract

This invention relates to a composition containing quercetin, vitamin B3, vitamin C, and folic acid. Also disclosed is a method of using the composition for enhancing physical or mental performance or treating various diseases or disorders.

Claims

1. A composition comprising quercetin, vitamin B3, vitamin C and folic acid, wherein a weight ratio between quercetin, vitamin B3, and vitamin C is 1:

0.02-1;

0.2-2.5.

2. The composition of claim 1, wherein the weight ratio is 1:

0.05-0.2;

0.5-1.

3. The composition of claim 1, wherein the weight ratio is 1:

0.1-0.2;

0.5-1.

4. The composition of claim 1, wherein the weight ratio is 1:

0.04;

1.

5. The composition of claim 1, wherein the weight ratio is 1:

0.08;

1.

6. The composition of claim 1, wherein the composition is in dry form.

7. The composition of claim 1, wherein the composition is in liquid form.

8. The composition of claim 1, wherein the composition is a food product.

9. The composition of claim 8, wherein the food is tea, soft drinks, juice, milk, coffee, jelly, ice cream, yogurt, cookies, cereals, chocolates, or snack bars.

10. The composition of claim 1, wherein the composition is a dietary supplement or a pharmaceutical formulation.

11. The composition of claim 10, wherein the composition is a tablet, a capsule, a soft chew, or a gel.

18. A method enhancing physical or mental performance, comprising administering to a subject in need thereof an effective amount of the composition of claim 1.

20. A method for treating a disorder associated with C-reactive protein, comprising administering to a subject in need thereof an effective amount of the composition of claim 1.

22. A method for lowering cholesterol levels, comprising administering to a subject in need thereof an effective amount of the composition of claim 1.

24. A method for treating a disease or disorder, comprising administering to a subject in need thereof an effective amount of the composition of claim 1;

wherein the diseases or disorder is autoimmune disease, skin disease, lung disease, prostatitis inflammatory disease, arthritis, tumor, diabetes, sexual dysfunction, chronic constipation, infection, or neurodegenerative disease.

12. A composition consisting essentially of quercetin, vitamin B3, vitamin C and folic acid.

13. The composition of claim 12, wherein a weight ratio between quercetin, vitamin B3, and vitamin C is 1:

0.02-1;

0.2-2.5.

14. The composition of claim 12, wherein the weight ratio is 1:

0.05-0.2;

0.5-1.

15. The composition of claim 12, wherein the weight ratio is 1:

0.1-0.2;

0.5-1.

16. The composition of claim 12, wherein the weight ratio is 1:

0.04;

1.

17. The composition of claim 12, wherein the weight ratio is 1:

0.08;

1.

19. A method enhancing physical or mental performance, comprising administering to a subject in need thereof an effective amount of the composition of claim 12.

21. A method for treating a disorder associated with C-reactive protein, comprising administering to a subject in need thereof an effective amount of the composition of claim 12.

23. A method for lowering cholesterol levels, comprising administering to a subject in need thereof an effective amount of the composition of claim 12.

25. A method for treating a disease or disorder, comprising administering to a subject in need thereof an effective amount of the composition of claim 12;

wherein the diseases or disorder is autoimmune disease, skin disease, lung disease, prostatitis inflammatory disease, arthritis, tumor, diabetes, sexual dysfunction, chronic constipation, infection, or neurodegenerative disease.