Quercetin-containing compositions

• US 8,901,109 B2
• Filed: 06/23/2010
• Issued: 12/02/2014
• Est. Priority Date: 07/17/2006
• Status: Active Grant

• Current Assignee: Quercis Pharma AG
• Original Assignee: Quercegen Pharmaceuticals LLC
• Inventors: Lines, Thomas Christian
• Primary Examiner(s): Weddington, Kevin E
• Application Number:
  US12/821,287
• Publication Number:
  US 20100331337A1
• Time in Patent Office: 1,623 Days
• Field of Search: 514/183, 514/355, 514/457, 514/474
• US Class Current: 514/183
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/352 condensed with carbocyclic rings, e.g. methantheline cannabinoids A61K31/658
• CPC Class Codes: A61K 31/375 Ascorbic acid, i.e. vitamin C; Salts thereof
• CPC Class Codes: A61K 31/445 Non condensed piperidines, e.g. piperocaine
• CPC Class Codes: A61K 45/06 Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• CPC Class Codes: A61P 1/00 Drugs for disorders of the alimentary tract or the digestive system
• CPC Class Codes: A61P 11/00 Drugs for disorders of the respiratory system
• CPC Class Codes: A61P 15/00 Drugs for genital or sexual disorders for disorders of sex hormones A61P5/24; Contraceptives
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 19/02 for joint disorders, e.g. arthritis, arthrosis
• CPC Class Codes: A61P 25/28 for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• CPC Class Codes: A61P 29/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
• CPC Class Codes: A61P 3/00 Drugs for disorders of the metabolism of the blood or the extracellular fluid A61P7/00
• CPC Class Codes: A61P 3/10 for hyperglycaemia, e.g. antidiabetics
• CPC Class Codes: A61P 31/00 Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
• CPC Class Codes: A61P 31/04 Antibacterial agents
• CPC Class Codes: A61P 31/12 Antivirals
• CPC Class Codes: A61P 35/00 Antineoplastic agents
• CPC Class Codes: A61P 37/00 Drugs for immunological or allergic disorders
• CPC Class Codes: A61P 37/06 Immunosuppressants, e.g. drugs for graft rejection
• CPC Class Codes: A61P 9/00 : Drugs for disorders of the cardiovascular system
• CPC Class Codes: C07D 213/80 : in position 3

Abstract

This invention relates to a composition containing quercetin, vitamin B3, vitamin C, and folic acid. Also disclosed is a method of using the composition for enhancing physical or mental performance or treating various diseases or disorders.

Claims

1. A method for treating a disease or disorder, comprising administering to a subject in need thereof an effective amount of a composition consisting essentially of quercetin, vitamin B3, vitamin C, and folic acid;

wherein the disease or disorder is thyroiditis, rheumatoid arthritis, myositis, lupus, Celiac disease, eczema, urticaria, psoriasis, asthma, pulmonary fibrosis, chronic obstructive pulmonary disease, prostatitis, Crohn'"'"'s disease, ulcerative colitis, arthritis, leukemia, colon cancer, prostate cancer, kidney cancer, liver cancer, breast cancer, lung cancer, type II diabetes, sexual dysfunction, chronic constipation, influenza, human immunodeficiency virus infection, or herpes simplex virus infection.

2. The method of claim 1, wherein a weight ratio between quercetin, vitamin B3, and vitamin C is 1:

0.02-1;

0.2-2.5.

3. The method of claim 2, wherein the weight ratio is 1:

0.05-0.2;

0.5-1.

4. The method of claim 2, wherein the weight ratio is 1:

0.1-0.2;

0.5-1.

5. The method of claim 2, wherein the weight ratio is 1:

0.04;

1.

6. The method of claim 2, wherein the weight ratio is 1:

0.08;

1.

7. The method of claim 1, wherein the composition is in dry form.

8. The method of claim 7, wherein a weight ratio between quercetin, vitamin B3, and vitamin C is 1:

0.02-1;

0.2-2.5.

9. The method of claim 8, wherein the weight ratio is 1:

0.05-0.2;

0.5-1.

10. The method of claim 8, wherein the weight ratio is 1:

0.1-0.2;

0.5-1.

11. The method of claim 8, wherein the weight ratio is 1:

0.04;

1.

12. The method of claim 8, wherein the weight ratio is 1:

0.08;

1.

13. The method of claim 1, wherein the composition is in liquid form.

14. The method of claim 13, wherein a weight ratio between quercetin, vitamin B3, and vitamin C is 1:

0.02-1;

0.2-2.5.

15. The method of claim 14, wherein the weight ratio is 1:

0.05-0.2;

0.5-1.

16. The method of claim 14, wherein the weight ratio is 1:

0.1-0.2;

0.5-1.

17. The method of claim 14, wherein the weight ratio is 1:

0.04;

1.

18. The method of claim 14, wherein the weight ratio is 1:

0.08;

1.

19. The method of claim 1, wherein the composition is a food product.

20. The method of claim 19, wherein the food product is tea, soft drinks, juice, milk, coffee, jelly, ice cream, yogurt, cookies, cereals, chocolates, or snack bars.

21. The method of claim 1, wherein the composition is a dietary supplement or a pharmaceutical formulation.

22. The method of claim 21, wherein the composition is a tablet, a capsule, a soft chew, or a gel.