DRAINAGE SYSTEMS FOR EXCESS BODY FLUIDS AND ASSOCIATED METHODS

• US 20120302938A1
• Filed: 06/04/2012
• Published: 11/29/2012
• Est. Priority Date: 03/19/2010
• Status: Abandoned Application

• Current Assignee: University of Washington
• Original Assignee: University of Washington
• Inventors: Lutz, Barry R., Browd, Samuel R.
• Application Number:
  US13/488,326
• Publication Number:
  US 20120302938A1
• Time in Patent Office: Days
• US Class Current: 604/9
• CPC Class Codes: A61B 5/031 Intracranial pressure
• CPC Class Codes: A61M 2027/004 with at least a part of the circuit outside the body
• CPC Class Codes: A61M 2039/226 Spindles or actuating means
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 27/002 Implant devices for drainage of body fluids from one part of the body to another intraocular A61F9/00781; middle ear A61F11/202
• CPC Class Codes: A61M 27/006 Cerebrospinal drainage; Accessories therefor, e.g. valves
• CPC Class Codes: A61M 39/284 Lever clamps

Abstract

Drainage systems for excess body fluids and associated methods are disclosed herein. A body fluid drainage system in accordance with an embodiment of the present technology, for example, can include a catheter having an exterior surface, a proximal portion, and a distal portion. The body fluid drainage system can further include a valve device, a pressure sensor, and a controller operatively coupled to the valve device and the pressure sensor. The valve device can include an actuator positioned over the exterior surface of the catheter. The actuator is movable between an open position that allows body fluid flow through the catheter, a closed position that at least substantially obstructs the body fluid flow through the catheter, and intermediate positions that partially obstruct the body fluid flow through the catheter. The controller can change the position of the actuator in response to a predetermined condition of the pressure sensor.

Claims

1-3. -3. (canceled)

11. (canceled)

25. (canceled)

26. A body fluid drainage system, comprising:

a catheter having an exterior surface, a proximal portion, and a distal portion opposite the proximal portion;

a valve device having a first actuator over the catheter, wherein the first actuator is configured to apply incremental force to the exterior surface of the catheter to regulate body fluid flow through the catheter;

a pressure sensor;

,

a controller operatively coupled to the valve device and the pressure sensor, the controller being configured to change the force applied to the catheter by the first actuator in response to a predetermined condition of the pressure sensor;

a reservoir between the proximal and the distal portions of the catheter, the reservoir having a cross-sectional dimension greater than a cross-sectional dimension of the proximal and distal portions of the catheter; and

a second actuator over the reservoir.

4. The body fluid drainage system of claim 26 wherein the proximal portion, the distal portion, and the reservoir are a single lumen.

5. The body fluid drainage system of claim 26 wherein the valve device comprises at least one pinch valve.

6. The body fluid drainage system of claim 26 wherein the actuator comprises at least one of a linear actuator, a cam actuator, and a lever actuator.

7. The body fluid drainage system of claim 26 wherein the valve device comprises an interface member between the first actuator and the exterior surface of the catheter.

8. The body fluid drainage system of claim 7 wherein the interface member comprises a compliant member.

9. The body fluid drainage system of claim 26, further comprising:

a magnetic shield over the valve device and the controller, the magnetic shield at least substantially obstructing magnetic interference with the valve device and the controller.

10. The body fluid drainage system of claim 26 wherein the catheter comprises peristaltic pump tubing proximate to the first actuator.

12. The body fluid drainage system of claim 26 wherein the first actuator fails in the open position.

13. The body fluid drainage system of claim 26 wherein the controller is configured to change the position of the first actuator in response to at least one of a predetermined intracranial pressure and a predetermined body fluid flow rate through the catheter.

14. The body fluid drainage system of claim 26, further comprising an orientation sensor operably coupled to the controller, wherein the orientation sensor is configured to monitor positional changes of the body fluid drainage system.

15. The body fluid drainage system of claim 14 wherein the orientation sensor comprises at least one of an accelerometer and an inclinometer.

16. The body fluid drainage system of claim 26 wherein the pressure sensor is a first pressure sensor, and wherein the body fluid drainage system further comprises:

a tube having a first end portion and a second end portion opposite the first end portion;

an end cap at the first end portion;

a second pressure sensor at the second end portion; and

a reference fluid in the tube, the reference fluid having a density substantially similar to a density of body fluid.

17. The body fluid drainage system of claim 26, further comprising:

a controller interface coupled to the controller, the controller interface being configured to selectively monitor at least one of intracranial pressure and body fluid flow rate.

18. The body fluid drainage system of claim 26, further comprising a wireless communication link coupled to the controller.

19. The body fluid drainage system of claim 26 wherein the catheter comprises an antibiotic impregnated material.

20. The body fluid drainage system of claim 26, further comprising an electro-osmotic pump coupled to the catheter and configured to increase body fluid flow rate through the catheter.

21. The body fluid drainage system of claim 26, further comprising a flow rate sensor operatively coupled to the controller and configured to sense the body fluid flow rate through the catheter.

22. The body fluid drainage system of claim 21 wherein the flow rate sensor comprises at least one of a Rotameter, a resistive electrical heater and a temperature sensor embedded in the body fluid flow, a tick-tock chamber, and an external sensor device outside the body fluid flow.

23. The body fluid drainage system of claim 26, further comprising:

a power source operatively coupled to the controller and at least one of the first or second actuators, wherein the first and/or second actuators is-are configured to use the power source only when the first and/or second actuators changes position.

24. The body fluid drainage system of claim 26 wherein the first actuator is configured to hold the open position, the closed position, and the intermediate positions without power.

27. The body fluid drainage system of claim 26 wherein:

the reservoir has a first length between the proximal and distal portions of the catheter; and

the second actuator has a second length at least substantially equal to the first length.

28. The body fluid drainage system of claim 26, comprising:

a third actuator over the distal portion of the catheter, wherein the third actuator is configured to apply incremental force to the exterior surface of the distal portion of the catheter to regulate body fluid flow through the catheter, and wherein the controller is configured to incrementally change the force applied by the first and second actuators independently of one another.

29. (canceled)

30. A fluid control device, comprising:

a catheter configured to be implanted into a body of a patient and in fluid communication with an area of excess body fluid, the catheter having an exterior surface, a proximal portion, and a distal portion opposite the proximal portion;

an actuator over the catheter; and

an interface member between the actuator and the exterior surface of the catheter, wherein the interface member comprises a compliant member

wherein the actuator is configured to exert force on the interface member to regulate flow rate through the catheter.

31. The fluid control device of claim 30 wherein the compliant member comprises at least one of a spring and a flexible lever, the flexible lever having a fulcrum proximate to the exterior surface of the catheter.

32. The fluid control device of claim 30 wherein the actuator comprises at least one of a linear actuator, a rotary actuator, and a lever actuator.

33. The fluid control device of claim 30 wherein:

the actuator comprises a rotating actuator; and

the compliant member comprises a flexible lever, wherein the rotating actuator is configured to rotate the lever around a fulcrum proximate to the exterior surface of the catheter.

34. The fluid control device of claim 30 wherein the actuator is a first actuator, the first actuator is over the proximal portion of the catheter, and the flow control device further comprises:

a reservoir between the proximal and distal portions of the catheter, the reservoir portion having an exterior surface and a cross-sectional dimension greater than a cross-sectional dimension of the proximal and distal portions;

a second actuator over the reservoir, wherein the second actuator is configured to apply force to the exterior surface of the reservoir;

a third actuator over the distal portion of the catheter, wherein the third actuator is configured to apply incremental force to the exterior surface of the distal portion of the catheter to regulate body fluid flow through the catheter; and

a controller operatively coupled to the first, second, and third actuators, the controller changing the force applied by the first, second, and third actuators to the catheter and the reservoir.

35-61. -61. (canceled)