PERCUTANEOUSLY DELIVERABLE VALVES

• US 20130190860A1
• Filed: 06/15/2011
• Published: 07/25/2013
• Est. Priority Date: 06/15/2010
• Status: Abandoned Application

• Current Assignee: Mayo Foundation For Medical Education And Research (Mayo Clinic)
• Original Assignee: Mayo Foundation For Medical Education And Research (Mayo Clinic)
• Inventors: Sundt, Thoralf M. III
• Application Number:
  US13/704,197
• Publication Number:
  US 20130190860A1
• Time in Patent Office: Days
• US Class Current: 623/2.13
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2445 Annuloplasty rings in direct contact with the valve annulus
• CPC Class Codes: A61F 2/2457 Chordae tendineae prostheses
• CPC Class Codes: A61F 2/2469 with resilient valve members, e.g. conical spiral
• CPC Class Codes: A61F 2230/0067 conical

Abstract

This document provides methods and materials related to providing a mammal with a replacement valve (e.g., a synthetic or artificial heart valve). For example, synthetic or artificial heart valve that can be delivered in a minimally invasive manner are provided.

Claims

1. An artificial heart valve for placement within a mammal, wherein said heart valve comprises:

(a) at least two struts having a proximal portion and a distal portion, wherein said proximal portion is configured to attach to heart tissue, and wherein said struts, when said heart valve is placed within said mammal, converge towards an axis in a direction from said proximal portion to said distal portion, and

(b) a membrane structure attached to said struts and configured to form a wall around said axis, wherein at least a portion of said membrane structure is capable of expanding and collapsing movement, wherein during said expanding movement said portion of said membrane structure moves away from said axis to form a closed position of said heart valve, wherein during said collapsing movement said portion of said membrane structure moves toward said axis to form an opened position of said heart valve,

wherein, when said heart valve is placed within said mammal and in said opened position, blood upstream of said heart valve is capable of moving past said heart valve between said membrane structure and the mammal'"'"'s heart tissue, and wherein, when said heart valve is placed within said mammal and in said closed position, movement of blood upstream of said heart valve past said heart valve between said membrane structure and the mammal'"'"'s heart tissue is limited.

2. The heart valve of claim 1, wherein said mammal is a human.

3. The heart valve of claim 1, wherein said proximal portion of said struts is configured to attach to heart tissue via an adhesive, clamp, staple, barb, suture, hook, screw, or combination thereof.

4. The heart valve of claim 1, wherein said membrane structure comprises flexible biocompatible material.

5. The heart valve of claim 1, wherein said membrane structure comprises a polymer.

6. The heart valve of claim 1, wherein said membrane structure comprises animal pericardium tissue.

7. The heart valve of claim 1, wherein said membrane structure forms a conical shape.

8. The heart valve of claim 1, wherein said membrane structure forms a conical shape defining a lumen comprising an opening at first end and an opening at a second end, wherein the opening at said first end is larger than the opening at said second end.

9. The heart valve of claim 1, wherein said heart valve comprises a first end defining a diameter and a second end defining a diameter, wherein the diameter of said first end is larger than the diameter of the second end, and wherein said first end defines an opening.

10. The heart valve of claim 9, wherein said second end defines an opening, wherein the opening of said second is smaller than the opening at said first end.

11. The heart valve of claim 1, wherein said struts comprise flexible material.

12. The heart valve of claim 1, wherein said struts comprises a shape memory material.

13. The heart valve of claim 12, wherein said shape memory material is nitinol.

14. The heart valve of claim 1, wherein said heart valve is capable of being placed within said mammal percutaneously.

15. The heart valve of claim 1, wherein said heart valve is capable of moving from a collapsed position during delivery to said mammal to an expanded position after placement within said mammal.

16. The heart valve of claim 1, wherein said heart valve comprises a ring structure attached to said proximal portion of said struts.

17. The heart valve of claim 16, wherein, when said heart valve is placed within said mammal and in said opened position, blood upstream of said heart valve is capable of moving past said heart valve between said membrane structure and said ring structure, and wherein, when said heart valve is placed within said mammal and in said closed position, movement of blood upstream of said heart valve past said heart valve between said membrane structure and said ring structure is limited.

18. The heart valve of claim 16, wherein said ring structure comprises a shape memory material biased to promote movement of said proximal portion of said struts away from said axis during placement of said heart valve within said mammal.

19. The heart valve of claim 1, wherein said heart valve comprises a ring structure attached to said distal portion of said struts.

20. The heart valve of claim 1, wherein said heart valve comprises a tethering cord anchor.

21. The heart valve of claim 20, wherein said tethering cord anchor is configured to extend from said heart valve and across at least a portion of the heart chamber downstream of said heart valve when said heart valve is placed within said mammal.

22. The heart valve of claim 21, wherein said tethering cord anchor comprises an adhesive, clamp, staple, barb, suture, hook, screw, or combination thereof configured to attach said tethering cord anchor to a wall of said heart chamber.