HUMAN PLACENTAL COLLAGEN COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME
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Abstract
The present invention provides compositions comprising human placental telopeptide collagen, methods of preparing the compositions, methods of their use and kits comprising the compositions. The compositions, kits and methods are useful, for example, for augmenting or replacing tissue of a mammal.
18 Citations
67 Claims
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1-48. -48. (canceled)
- 49. A method of treating a wound comprising contacting the wound with a composition comprising placental extracellular matrix, wherein said composition comprises at least 80% collagen by dry weight and wherein said composition comprises at least 10% elastin by dry weight.
- 54. A method of augmenting tissue repair in a subject comprising contacting said tissue with a composition comprising placental extracellular matrix, wherein said composition comprises at least 80% collagen by dry weight and wherein said composition comprises at least 10% elastin by dry weight.
- 57. A method of replacing tissue of a subject, comprising administering to the subject a composition comprising placental extracellular matrix, wherein said composition comprises at least 80% collagen by dry weight and wherein said composition comprises at least 10% elastin by dry weight.
- 59. A nerve guide comprising a composition comprising placental extracellular matrix, wherein said composition comprises at least 80% collagen by dry weight and wherein said composition comprises at least 10% elastin by dry weight.
- 61. A method of treating a dental defect or disease in a subject comprising applying to the site of the defect or disease a composition comprising placental extracellular matrix, wherein said composition comprises at least 80% collagen by dry weight and wherein said composition comprises at least 10% elastin by dry weight.
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64. A method of replacing lost, damaged or diseased gingival tissue in a subject comprising applying to the site of the lost, damaged or diseased gingival tissue a composition comprising placental extracellular matrix, wherein said composition comprises at least 80% collagen by dry weight and wherein said composition comprises at least 10% elastin by dry weight.
- 65. A solution comprising a composition comprising placental extracellular matrix, wherein said composition comprises at least 80% collagen by dry weight and wherein said composition comprises at least 10% elastin by dry weight.
Specification