METHOD FOR CALCULATING OR APPROXIMATING ONE OR MORE VALUES REPRESENTING PARAMETERS OF A PATIENT AND DEVICES

• US 20130277287A1
• Filed: 12/09/2011
• Published: 10/24/2013
• Est. Priority Date: 12/09/2010
• Status: Active Grant

• Current Assignee: Fresenius Medical Care Deutschland GmbH (Fresenius Medical Care AG)
• Original Assignee: Fresenius Medical Care Deutschland GmbH (Fresenius Medical Care AG)
• Inventors: Moissl, Ulrich, Wieskotten, Sebastian, Chamney, Paul, Nier, Volker, Wabel, Peter
• Granted Patent: US 10,092,685 B2
• Time in Patent Office: Days
• US Class Current: 210/96.2
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1613 Profiling or modelling of patient or predicted treatment evolution or outcome
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 20/40 relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16H 50/50 for simulation or modelling of medical disorders

Abstract

A method for calculating or estimating or approximating one or more values representing parameters of a patient includes the step of interpolating or extrapolating of at least one later value of a first parameter taking into account at least one earlier value of the first parameter, at least one earlier and at least one later value of a second parameter, and a mathematical relation between the first and the second parameter. An apparatus, a blood treatment device, a digital storage device, a computer program product, and a computer program are also described.

Claims

1-18. -18. (canceled)

19. A method for calculating or estimating or approximating one or more values representing parameters of a patient, the method comprising:

interpolating or extrapolating of at least one later value of a first parameter, taking into account;

at least one earlier value of the first parameter,

at least one earlier and at least one later value of a second parameter, and

a mathematical relation between the first and the second parameters.

20. The method according to claim 19, wherein the first, the second and further parameters are selected from a group of parameters, the group comprising at least haematocrit (HTC), blood water content (BWC), extracellular water content (EWC), blood volume (BV), blood volume at a beginning of a treatment session (BV_start), normohydrated blood volume (BV₀), overhydration (OH), relative overhydration (relOH), normoweight (Normwgt), preweight (before treatment), postweight (after treatment), haemoglobin mass (mass_Hb), and haemoglobin concentration in blood (Hb).

21. The method according to claim 19, further comprising minimizing a mathematical error.

22. The method according to claim 19, further comprising minimizing a square error.

23. The method according to claim 19, further comprising weighting one or more of the earlier values.

24. The method according to claim 19, further comprising weighting values or mean values derived from values of one or more parameters estimated and measured earlier.

25. The method according to claim 19, further comprising using a mathematical filter, a regression analysis or neuronal networks.

26. The method according to claim 19, further comprising using a linear filter, a non-linear filter, a Kalman filter, an unscented Kalman filter, a Kalman-Bucy filter, a hybrid Kalman filter or an extended Kalman filter.

27. The method according to claim 19, further comprising using a filter that works partly or completely recursively.

28. An apparatus configured to carry out the method according to claim 19.

29. The apparatus according to claim 28, further comprising an output device for outputting results provided by carrying out the method.

30. The apparatus according to claim 28, configured to control a device for treating a patient'"'"'s blood in accordance with or based on the one or more values calculated or approximated or estimated by the method.

31. A blood treatment device, comprising at least one apparatus according to claim 28.

32. The device according to claim 31, configured for treating a patient by means of dialysis.

33. The device according to claim 32, configured for treating a patient by haemofiltration, ultrafiltration, and/or haemodialysis.

34. A non-transitory computer-readable storage medium with an executable program stored thereon, wherein the program instructs a programmable computer system so as to execute the steps of the method according to claim 19.