COMPOSITION OF PLANT EXTRACT AND ITS PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF

• US 20170157194A1
• Filed: 08/28/2015
• Published: 06/08/2017
• Est. Priority Date: 08/28/2014
• Status: Active Grant

• Current Assignee: Caliway Biopharmaceuticals Co., Ltd.
• Original Assignee: Caliway Biopharmaceuticals Co., Ltd.
• Inventors: LING, Yu-Fang
• Granted Patent: US 10,537,605 B2
• Time in Patent Office: Days
• CPC Class Codes: A61K 2121/00 Preparations for use in therapy
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/05 Phenols cannabinoids A61K31/658
• CPC Class Codes: A61K 36/82 Theaceae (Tea family), e.g. camellia
• CPC Class Codes: A61K 36/9066 Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
• CPC Class Codes: A61K 9/0019 Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner non-active ingredients are additionally classified in A61K47/00
• CPC Class Codes: A61K 9/0053 Mouth and digestive tract, i.e. intraoral and peroral administration rectal administration A61K9/0031
• CPC Class Codes: A61K 9/0095 Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches A61K9/0007 takes precedence; eatable gels or foams A61K9/0056; oral mucosa adhesive forms A61K9/006

Abstract

Provided is a plant extract composition and a pharmaceutical composition thereof for reducing body weight and body fat, wherein the plant extract composition comprises a green tea extract and a turmeric extract respectively 30 wt % to 75 wt % and 20 wt % to 55 wt % of a total weight of the composition. In diet-induced obesity models, either obesity is induced first or simultaneously with administration, the plant extract composition and a pharmaceutical composition thereof can reduce body weight and body fat more significantly than a single plant extract or commercially available weight loss drugs.

Claims

1. A plant extract composition for reducing body weight and body fat, wherein the composition comprises a green tea extract and a turmeric extract, and the percentages of green tea extract and turmeric extract are respectively 30 wt % to 75 wt % and 20 wt % to 55 wt % of a total weight of the composition.

3. A method of using the composition as claimed in claim 1 for reducing body weight and body fat, comprising a step of administering the composition to a subject.

4. A pharmaceutical composition for reducing body weight and body fat, wherein the pharmaceutical composition comprises a therapeutically effective amount of the plant extract composition as claimed in claim 1 and a pharmaceutically acceptable carrier.

5. A method of using the pharmaceutical composition as claimed in claim 4 for reducing body weight and body fat, comprising a step of administering to a subject in need thereof a therapeutically effective amount of the pharmaceutical composition, wherein the subject is an animal or a human.

6. The method as claimed in claim 5, wherein the formulation of the pharmaceutical composition is orally administered or administered by injection.

7. The method as claimed in claim 6, wherein the therapeutically effective amount of the pharmaceutical composition for a human is from 1.8 mg/kg BW to 145 mg/kg BW.

8. The method as claimed in claim 7, wherein the therapeutically effective amount of the pharmaceutical composition for a human is from 5.4 mg/kg BW to 70 mg/kg BW.

2. (canceled)