PHARMACEUTICAL SPRAY COMPOSITION COMPRISING A VITAMIND D ANALOGUE AND A CORTICOSTEROID
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Abstract
A Pharmaceutical Spray Composition Comprising a Vitamin D Analogue and a Corticosteroid
The present invention relates to a topical spray composition comprising a biologically active vitamin D derivative or analogue and a corticosteroid, and its use in the treatment of dermal diseases and conditions.
3 Citations
53 Claims
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1-26. -26. (canceled)
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27. A sprayable, substantially anhydrous topical composition comprising
calcipotriol or calcipotriol monohydrate, betamethasone dipropionate, a pharmaceutically acceptable propellant, present in amount between 45-95% w/w of the total composition, a pharmaceutically acceptable lipid carrier, present in an amount between 5-55% w/w of the total composition, and a pharmaceutically acceptable antioxidant, wherein no more than 10% by weight of the calcipotriol or calcipotriol monohydrate has degraded after storage of the composition for 3 months at about 40°
Specification