Susceptibility genes for age-related maculopathy (ARM) on chromosome 10q26

  • US 7,695,909 B2
  • Filed: 06/07/2006
  • Issued: 04/13/2010
  • Est. Priority Date: 06/08/2005
  • Status: Active Grant
First Claim
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1. A method of determining risk of developing Age-Related Maculopathy in a human subject comprising detecting the presence of a thymine or guanine at base 270 of SEQ ID NO:

  • 20 (rs10490924) from a sample obtained from the subject, wherein the presence of thymine for one or both alleles indicates increased risk of developing Age-Related Maculopathy and the presence of guanine for both alleles indicates decreased risk of developing Age-Related Maculopathy.

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