Transcutaneous analyte sensor

  • US 7,774,145 B2
  • Filed: 01/18/2006
  • Issued: 08/10/2010
  • Est. Priority Date: 08/01/2003
  • Status: Active Grant
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First Claim
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1. A device for monitoring glucose concentration in a host, the device comprising:

  • a substantially continuous glucose sensor configured to produce sensor data indicative of a glucose concentration in a host;

    an integrated receiver configured to receive the sensor data from the substantially continuous glucose sensor, wherein the integrated receiver comprises;

    an in vitro single point glucose monitor configured to receive a biological sample from the host and to measure a glucose concentration in the sample;

    a processor module; and

    a computer readable memory comprising;

    instructions configured to cause the processor module to calibrate the sensor data received from the substantially continuous glucose sensor;

    instructions configured to cause the processor module to determine a rate of change of the calibrated sensor data, to determine whether the rate of change is within a range of rates of change delimited by maximum normally sustainable rates of change of glucose in humans, and to not allow the processor module to calibrate the sensor data when the rate of change is outside the range;

    instructions configured to cause the processor module to estimate at least one projected glucose concentration value based at least in part on a linear extrapolation of calibrated sensor data and on a variation analysis; and

    instructions configured to cause the processor module to activate an alarm when the projected glucose concentration value is greater than a high threshold value or less than a low threshold value.

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