Intramedullary access or infusion devices

• US 7,833,204 B2
• Filed: 05/13/2008
• Issued: 11/16/2010
• Est. Priority Date: 05/14/2007
• Status: Active Grant

• Current Assignee: Everest Holdings LLC
• Original Assignee: Applied Medical Research
• Inventors: Picha, George J.
• Primary Examiner(s): Sirmons; Kevin C
• Assistant Examiner(s): Hall; Deanna K
• Application Number:
  US12/119,867
• Publication Number:
  US 20080287910A1
• Time in Patent Office: 917 Days
• Field of Search: 604/288.01, 604/288.02, 604/288.03, 604/288.04, 604/16, 604/40, 623/16.11, 623/17.12, 606/92
• US Class Current: 604/288.01
• CPC Class Codes: A61B 17/3472 for bones, e.g. intraosseus injections
• CPC Class Codes: A61M 2210/02 Bones
• CPC Class Codes: A61M 39/0208 Subcutaneous access sites for injecting or removing fluids transcutaneous access sites A61M39/0247; implantable infusion devices A61M5/14276
• CPC Class Codes: A61M 39/04 having pierceable self-sealing members

Abstract

Intramedullary access or infusion devices that includes a tubular conduit having a distal end and a proximal end with a length sufficient to pass through the cortical region to the cancellous region of a bone; a flange circling the outside of the proximal end of the conduit; and a penetrable diaphragm positioned within the tubular conduit, are described. The devices may be placed in bone and later used, for example, as a site for administering a pharmacologically active agent.

Claims

1. An intramedullary infusion device, comprising:

a tubular conduit having a distal end and a proximal end with a length sufficient to pass through the cortical region and extend into the cancellous region of a bone;

wherein the tubular conduit is closed at the distal end;

a flange circling the outside of the proximal end of the conduit;

a penetrable diaphragm positioned within the tubular conduit;

a plurality of outlet structures positioned along the outer side surfaces of the tubular conduit, wherein an outlet structure creates an outlet opening so as to allow fluid flow between the tubular conduit and the cancellous region of the bone; and

a compressible member positioned over the outlet openings at the distal end of the tubular conduit, wherein the compressible member comprises an elastomer.

2. The intramedullary infusion device of claim 1, wherein the outlet openings are positioned on outlet structures that extend beyond the surface of the tubular conduit.

3. The intramedullary infusion device of claim 1, wherein the outside of the tubular conduit includes surface texturing.

4. The intramedullary infusion device of claim 1, wherein the outside of the tubular conduit includes threading.

5. The intramedullary infusion device of claim 4, wherein the threading comprises micropillars.

6. The intramedullary infusion device of claim 1, wherein the device further comprises a sensor.

7. An intramedullary infusion device, comprising:

a tubular conduit having a distal end and a proximal end with a length sufficient to pass through the cortical region and extend into the cancellous region of a bone;

wherein the tubular conduit is closed at the distal end;

a flange circling the outside of the proximal end of the conduit;

a penetrable diaphragm positioned within the tubular conduit;

a plurality of outlet structures positioned along the outer side surfaces of the tubular conduit, wherein an outlet structure creates an outlet opening so as to allow fluid flow between the tubular conduit and the cancellous region of the bone; and

a compressible member positioned over the outlet openings at the distal end of the tubular conduit, wherein the compressible member comprises a spring-loaded diaphragm.

8. The intramedullary infusion device of claim 7, wherein the outside of the tubular conduit includes surface texturing.

9. The intramedullary infusion device of claim 7, wherein the outside of the tubular conduit includes threading.

10. The intramedullary infusion device of claim 9, wherein the threading comprises micropillars.

11. The intramedullary infusion device of claim 7, wherein the device further comprises a sensor.

12. The intramedullary infusion device of claim 7, wherein the outlet openings are positioned on outlet structures that extend beyond the surface of the tubular conduit.

13. The intramedullary infusion device of claim 7, wherein the compressible member comprises an elastomer.