Diagnostic methods

  • US 8,455,194 B2
  • Filed: 02/29/2012
  • Issued: 06/04/2013
  • Est. Priority Date: 02/29/2008
  • Status: Active Grant
First Claim
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1. A method, comprising:

  • (a) assaying for the presence or absence of a C or T allele for single nucleotide polymorphism rs4149056 in the SLCO1B1 gene in a biological sample obtained from a patient in need of treatment with a statin;

    (b) correlating the identity of the allele of said polymorphism with risk of statin-induced myopathy;

    (c) establishing a statin type and dosage based on said patient'"'"'s statin-induced myopathy risk; and

    (d) administering said statin type and dosage to said patient.

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