Method, system, and computer program product for the detection of physical activity by changes in heart rate, assessment of fast changing metabolic states, and applications of closed and open control loop in diabetes
First Claim
1. A computer-implemented method for detecting physical activity of a patient and its effects on metabolic demand of the metabolic system of said patient, comprising:
- detecting onset of the physical activity using changes in heart rate data of said patient; and
evaluating effects of physical activity on glucose demand of the metabolic system of said patient, wherein said evaluation is determined by the following steps;
calculating, by a processor, deviations of heart rate values and blood glucose values from basal heart rate values and basal blood glucose values;
calculating, by a processor, a quantitative measure of short-term change in glucose demand due to said physical activity; and
calculating, by a processor, a short term change in glucose demand.
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Accused Products
Abstract
A method, system, and computer program product related to the detection of physical activity using changes in heart rate. The method, system, and computer program product evaluates short term glucose demand and long term insulin action due to physical activity. The method, system, and computer program product is further related to the improvement of open and closed loop control of diabetes by accounting for the metabolic changes due to physical activity. The method, system, and computer program product is directed to detecting in real time the short and long term effects of physical activity on insulin action via heart rate analysis, and recommending changes in insulin dosing to compensate for the effects of physical activity. With these recommendations, the open and closed loop control of diabetes can be improved and steps can be taken to prevent hypoglycemia that may result from increased insulin sensitivity due to physical activity.
40 Citations
243 Claims
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1. A computer-implemented method for detecting physical activity of a patient and its effects on metabolic demand of the metabolic system of said patient, comprising:
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detecting onset of the physical activity using changes in heart rate data of said patient; and evaluating effects of physical activity on glucose demand of the metabolic system of said patient, wherein said evaluation is determined by the following steps; calculating, by a processor, deviations of heart rate values and blood glucose values from basal heart rate values and basal blood glucose values; calculating, by a processor, a quantitative measure of short-term change in glucose demand due to said physical activity; and calculating, by a processor, a short term change in glucose demand. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 37)
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31. A computer-implemented method for detecting physical activity of a patient and its effects on metabolic demand of the metabolic system of said patient, comprising:
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acquiring glucose data, insulin delivery data and heart rate data; detecting, by a processor, onset of the physical activity using changes in the heart rate data; evaluating, by a processor, changes in insulin sensitivity and glucose demand of the metabolic system of said patient due to the physical activity; and indicating, by a processor, recommendations of insulin dosing. - View Dependent Claims (32, 33, 34, 35, 36, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81)
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82. A system for detecting physical activity of a patient and its effects on metabolic demand of the metabolic system of said patient, said system comprises:
a processor programmed to; detect onset of the physical activity of the patient using changes in heart rate data; and evaluate effects of physical activity on glucose demand of the metabolic system of said patient, wherein said evaluation is determined by the following steps; calculating deviations of heart rate values and blood glucose values from basal heart rate values and basal blood glucose values; calculating a quantitative measure of short-term change in glucose demand due to said physical activity; and calculating a short term change in metabolic demand. - View Dependent Claims (83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111)
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112. A system for detecting physical activity of a patient and its effects on metabolic demand of the metabolic system of said patient, said system comprising:
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an acquisition module acquiring glucose data, insulin delivery data and heart rate data; a processor programmed to; detect onset of the physical activity using changes in heart rate data; evaluate changes in insulin sensitivity and glucose demand of the metabolic system of the patient due to the physical activity; and indicate recommendations of insulin dosing. - View Dependent Claims (113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162)
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163. A computer program product comprising a non-transitory computer readable medium having computer executable instructions for detecting physical activity of a patient and its effects on metabolic demand of the metabolic system of said patient, said computer executable instructions comprising instructions for:
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detecting onset of the physical activity using changes in heart rate data; evaluating effects of physical activity on glucose demand of the metabolic system of the patient, wherein said evaluation is determined by the following steps; calculating deviations of heart rate values and blood glucose values from basal heart rate values and basal blood glucose values; calculating a quantitative measure of short-term change in glucose demand due to said physical activity; and calculating a short term change in glucose demand. - View Dependent Claims (164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192)
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193. A computer program product comprising a non-transitory computer readable medium having computer executable instructions for detecting physical activity and its effects on metabolic demand, said computer executable instructions comprising instructions for:
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acquiring glucose data, insulin delivery data and heart rate data; detecting onset of the physical activity using changes in heart rate data; evaluating changes in insulin sensitivity and glucose demand due to the physical activity; and indicating recommendations of insulin dosing. - View Dependent Claims (194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227, 228, 229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239, 240, 241, 242, 243)
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Specification